Sodium gradient-dependent phosphate transport in renal brush border membrane vesicles.
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چکیده
منابع مشابه
Sodium gradient-dependent L-glutamate transport in renal brush border membrane vesicles. Effect of an intravesicular > extravesicular potassium gradient.
A Na+ gradient (extravesicular > intravesicular) increased approximately 10 times the initial rate of Lglutamate transport into osmotically active renal brush border membrane vesicles and energized the transient accumulation of the amino acid against its concentration gradient. Stimulation of glutamate uptake was specific for Na'. Increasing the concentration of extravesicular Na' increased the...
متن کاملTaurine transport in renal brush-border-membrane vesicles.
Taurine transport in isolated brush-border-membrane vesicles from rat kidney is concentrative and it is driven by the Na+ gradient and transmembrane potential difference; binding is not a significant component of net uptake. The Na+-dependent component of net uptake is saturable with an apparent Km of 17 microM. The taurine-transport mechanism is selective for beta-amino compounds.
متن کاملThe sodium electrochemical potential-mediated uphill transport of D-glucose in renal brush border membrane vesicles.
The uphill transport of D-glucose in renal brush border membrane vesicles was correlated with the Na+ electrochemical gradient. Each component of the electrochemical potential, the membrane potential (outside positive) or the Na+ chemical gradient, when assayed independently, supported the concentrative uptake of the sugar. When the two components were combined, the rates of D-glucose uptake we...
متن کاملCyclic AMP-dependent protein phosphorylation in canine renal brush-border membrane vesicles is associated with decreased phosphate transport.
It is known that the administration of parathyroid hormone to dogs results in phosphaturia and decreased phosphate transport in brush-border vesicles isolated from the kidneys of those dogs. Parathyroid hormone has been shown to activate adenylate cyclase at the basal-lateral membrane of the renal proximal tubular cell. It has been postulated that parathyroid hormone-induced phosphaturia is eff...
متن کاملEnergetics of the Na+-dependent transport of D-glucose in renal brush border membrane vesicles.
The energetics of the Na+-dependent transport of D-glucose into osmotically active membrane vesicles, derived from the brush borders of the rabbit renal proximal tubule, was studied by determining how alterations in the electrochemical potential of the membrane induced by anions, ionophores, and a proton conductor affect the uptake of the sugar. The imposition of a large NaCl gradient (medium i...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 1981
ISSN: 0021-9258
DOI: 10.1016/s0021-9258(19)69840-6